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      HLS Therapeutics Announces Q4 and Year-End 2018 Financial Results


      News provided by

      HLS Therapeutics Inc.

      Mar 21, 2019, 06:30 ET

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      • Revenue of $61.4 million, Adjusted EBITDA of $41.1 million and Cash from Operations of $32.7 million for the year-ended December 31, 2018
      • REDUCE-IT™ cardiovascular outcomes study of Vascepa®, for which HLS has in-licensed exclusive Canadian rights, exceeded primary endpoint demonstrating an approximately 25% relative risk reduction in major adverse cardiovascular events
      • Debt refinancing co-led by JPMorgan Chase Bank, N.A. and Silicon Valley Bank; annual interest savings estimated at $10.0 million
      • Established a quarterly dividend policy of C$0.05 per common share
      • Subsequent to year-end, named experienced healthcare executive Laura A. Brege to the Board of Directors and Audit Committee
      • Subsequent to year-end, graduated to a listing on the Toronto Stock Exchange from the TSX-Venture Exchange

      TORONTO, March 21, 2019 /CNW/ - HLS Therapeutics Inc. ("HLS" or the "Company") (TSX: HLS), a specialty pharmaceutical company focusing on central nervous system and cardiovascular markets, announces its financial results for the three- and twelve-month periods ended December 31, 2018. Unless otherwise noted, all dollar amounts are expressed in United States ("U.S.") dollars.

      Q4 & FISCAL 2018 HIGHLIGHTS

      • Q4 2018 revenue was $16.7 million compared to $20.4 million in Q4 2017. Full year 2018 revenue was $61.4 million compared to $75.1 million in 2017. As expected, royalty revenue was lower in 2018, which accounts for the year-over-year change in revenue;
      • Q4 2018 Adjusted EBITDA was $11.2 million compared to $15.5 million in Q4 2017. Full year 2018 Adjusted EBITDA was $41.1 million compared to $55.9 million in 2017;
      • Q4 2018 cash from operations was $11.2 million compared to $8.9 million in Q4 2017. Full year 2018 cash from operations was $32.7 million compared to $27.2 million in 2017;
      • Q4 2018 net income of $0.4 million, or $0.01 per common share, compared to net loss of $(0.4) million, or $(0.02) per common share, in Q4 2017. Full year 2018 net loss of $(24.8) million, or $(0.92) per share, compared to net loss of $(6.1) million, or $(0.24) per common share in 2017. Net loss in 2018 included $19.0 million of one-time costs related to the debt refinancing, of which $12.2 million was a non-cash charge to expense the remaining unamortized costs associated with the previous debt agreement;
      • Amarin Corporation plc's ("Amarin") REDUCE-IT™ cardiovascular outcomes study of Vascepa®, for which HLS has in-licensed exclusive Canadian rights, exceeded its primary endpoint target demonstrating an approximately 25% relative risk reduction in major adverse cardiovascular events ("MACE") such as cardiovascular death, heart attack and stroke. Vascepa is not approved for use in Canada. HLS will file for approval with Health Canada following Amarin's supplemental filing with the FDA;
      • Refinanced outstanding senior secured debt; reduced the principal amount outstanding by $37.9 million and secured a lower interest rate, which are expected to result in annual interest expense savings of approximately $10.0 million. The refinancing was led by JPMorgan Chase, N.A. and Silicon Valley Bank and included a syndicate of Canadian Banks;
      • Established a quarterly dividend policy of $0.05 per outstanding common share; and
      • Completed reverse take-over onto the TSX Venture Exchange and began trading March 14, 2018.

      SUBSEQUENT TO YEAR-END

      • Graduated to the Toronto Stock Exchange on February 7, 2019;
      • Announced the in-licensing of the exclusive Canadian rights from Athelas Inc. for Athelas One, a medical device that may help to simplify the mandatory safety blood monitoring process for patients that are prescribed Clozaril®. Following its filing in January 2019, the device was accepted for review by Health Canada on March 13, 2019;
      • Amarin released new data showing that Vascepa provided a statistically significant 30% risk reduction in total (first and subsequent) cardiovascular events compared to placebo in the statin-treated patient population studied in REDUCE-IT;
      • Appointed experienced healthcare executive Laura A. Brege to the Board of Directors and Audit Committee, replacing Daniel Tassé who has accepted the CEO role at DBV Technologies; and
      • Declared a dividend of C$0.05 per outstanding common share to be paid on June 14, 2019, to shareholders of record as of April 30, 2019.

      "2018 was a busy and memorable year for HLS; one in which we continued to deliver solid financial performance while achieving a number of important developments in the growth and evolution of our business," said Greg Gubitz, CEO of HLS. "Early in the year, we went public on the TSX Venture Exchange bringing our story to a wider investor audience, and subsequent to year-end, we further expanded our potential investor audience by graduating to the Toronto Stock Exchange, Canada's premier exchange. With our strong cash flow generation, sound fundamentals and promising outlook we were able to successfully refinance our debt on terms that saw us reduce the principal outstanding by $37.9 million and reduce our interest rate, such that we will save approximately $10.0 million annually in interest expense. Finally, with a portion of those savings, we introduced a $0.05 per share quarterly dividend, which will return approximately $4.2 million per year to shareholders."

      "The key development of the year, however, was the release of positive results from Amarin's REDUCE-IT cardiovascular outcomes trial related to Vascepa (icosapent ethyl). These results were very strong as REDUCE-IT exceeded its primary endpoint demonstrating an approximately 25% relative risk reduction, to a high degree of statistical significance, in first occurrence of MACE. The results showed that patients taking Vascepa as an add-on to a statin in a population presenting a residual cardiovascular risk, demonstrated a 20% reduction in cardiovascular death, 31% reduction in heart attacks and 28% reduction in strokes when compared to a placebo. These are exceptional numbers and are on top of the benefits obtained from statin therapy."

      "Earlier this week, Amarin released positive new data that extends the scope of consistent effects of Vascepa beyond a patient's first cardiovascular event to all subsequent cardiovascular events, including cardiovascular death. The new data showed that Vascepa reduced total events—first and subsequent—by 30% compared to placebo, reflecting that 159 MACE events could be prevented for every 1,000 patients treated with Vascepa versus placebo over a five-year period. Also, this week, Amarin commented on data and analysis that underscores that people with elevated triglycerides without known cardiovascular disease could be at a high risk for cardiovascular events. Thus, elevated triglyceride levels may provide a means of identifying increased cardiovascular risk beyond cholesterol levels."

      "Overall, these results greatly exceeded our internal expectations suggesting that Vascepa has the potential to be a very significant drug for the treatment of patients with cardiovascular disease as well as a catalyst to drive significant organic growth in our business. With cardiovascular disease the leading cause of death worldwide, we look forward to bringing this important FDA-approved medication to Canadians. Vascepa is not approved for use in Canada and we expect to file for approval with Health Canada following Amarin's supplemental filing with the FDA."

      "Our momentum continued into 2019 with the recent announcement on a new initiative in the central nervous system therapeutic area, which has the potential to be synergistic to our Clozaril operations. Regarding Athelas One, or CSAN® ProntoTM as it would be branded in Canada, we look to bring to market a product that may help reduce the burden associated with the blood draw regimen for clozapine patients, which ultimately could help lower a barrier to a proven treatment for those who need it. Assuming it were to receive Health Canada approval, we believe CSAN Pronto can be a meaningful product for us. In terms of transaction details, Athelas will earn performance-based fees and milestone payments that are contingent on commercial success."

      DIVIDEND

      On March 20, 2019, the Company's Board of Directors declared a dividend of C$0.05 per outstanding common share to be paid on June 14, 2019, to shareholders of record as of April 30, 2019.

      These dividends paid on the Company's common shares are designated to be "eligible dividends" for purposes of section 89(1) of the Income Tax Act (Canada).

      BOARD OF DIRECTORS UPDATE

      Subsequent to year-end, Laura A. Brege, an experienced healthcare executive with an extensive public company background, was appointed to the HLS Board of Directors and will serve as a member of the Company's Audit Committee. Ms. Brege replaces Daniel Tassé, who has accepted the position of CEO at DBV Technologies and is stepping down from the HLS Board to focus his time on his new role.

      "We are very pleased to add an individual to our Board with the breadth of skills and background that Laura possesses," said William (Bill) Wells, Chairman of the Board of HLS. "Laura has extensive public company life sciences experience in the U.S. as both a C-level executive and as a Board member. We look forward to her insights and guidance as we execute further on our organic and acquisitive growth opportunities in both Canada and the U.S."

      Mr. Wells added: "At the same time, on behalf of the Board and management team, I would like to thank Daniel for his contributions as a Board member during a very busy and productive period for HLS and we wish him all the best in his future endeavors."

      Ms. Brege is Managing Director of Cervantes Life Science Partners, LLC., a health care advisory and consulting company. Prior to joining Cervantes Life Science Partners, Ms. Brege served as Chief Executive Officer and President of Nodality, Inc., a privately held biotechnology company focused in oncology and immunology from September 2012 to July 2015. Previously, Ms. Brege held several senior-level positions at Onyx Pharmaceuticals, Inc. from June 2006 to December 2011, including Executive Vice President and Chief Operating Officer. Before joining Onyx, Ms. Brege was a general partner at Red Rock Capital Management, a venture capital firm specializing in early stage financing for technology companies. Prior to Red Rock, she was Senior Vice President and Chief Financial Officer at COR Therapeutics. Earlier in her career, Ms. Brege served as Vice President and Chief Financial Officer at Flextronics and Vice President and Treasurer of The Cooper Companies. Ms. Brege serves on the boards of Acadia Pharmaceuticals (NASDAQ: ACAD), Aratana Therapeutics (NASDAQ: PETX), Pacira Pharmaceuticals (NASDAQ: PCRX), Portola Pharmaceuticals (NASDAQ: PTLA), and Dynavax Technologies (NASDAQ: DVAX). Ms. Brege earned her undergraduate degree from Ohio University and has an M.B.A. from the University of Chicago.

      FINANCIAL REVIEW

      Revenue

      The following table provides revenue segmentation by revenue type and geography for the three- and twelve-month periods ended December 31, 2018:


      Three months ended
      December 31,

      Twelve months ended
      December 31,


      2018

      2017

      2018

      2017






      Product sales





      Canada

      8,065

      7,600

      29,726

      28,637

      United States

      4,909

      4,077

      20,097

      18,801


      12,974

      11,677

      49,823

      47,438

      Royalty revenue

      3,687

      8,698

      11,592

      27,644


      16,661

      20,375

      61,415

      75,082

      Fourth quarter results are typically stronger than other quarters due to customer inventory dynamics that then resolve in the first quarter of the following year. In the Canadian market, where Clozaril is actively promoted and supported by a team of HLS employees, product sales increased by 6% and 4% in the fourth quarter and full-year, respectively. HLS believes that Clozaril is underutilized in the Canadian market relative to certain other comparable Western countries, which the Company believes presents a long-term growth opportunity for the product.

      In 2018, Clozaril continued to experience modest volume declines in the U.S. market, while gross sales were mitigated by a nominal price increase. Although increased seasonal demand in the fourth quarter moderated volume declines, product sales in the fourth quarter benefited primarily from lower than previously estimated expired product returns and increased efficiency in distribution programs under Company management. Full year product sales increased by 7% in the U.S. market as lower than estimated expired product returns and greater sales deduction efficiency were offset by lower authorized generic supplies.  

      Total revenue was lower year-over-year as royalty revenue declined in 2018 compared to 2017. Royalty revenue in 2017 benefited from competitive disruptions and the positive impact of a promotional campaign undertaken by the marketer of Absorica in the U.S. which provided windfall royalties in that year that reached a peak in Q4 2017. Royalty revenues in 2018 stabilized at levels that were more consistent with the pre-2017 period. On a sequential quarterly basis, royalty revenues for Q4 2018 were $3.7 million compared to $2.6 million in Q3 2018 reflecting, in part, that Q3 is traditionally a seasonally slower quarter for Absorica sales.

      Operating Expenses

      Operating expenses, which consist of cost of product sales, selling and marketing expense, medical, regulatory and patient support expense, and general and administrative expense, were $5.5 million in Q4 2018, compared to $4.9 million in Q4 2017. For the year-ended December 31, 2018, operating expenses were $20.3 million, compared to $19.2 million in 2017.

      Cost of product sales decreased in 2018 in-line with reduced authorized generic supplies and improved manufacturing costs as a result of the completion of the manufacturing transition for the U.S. market.

      The year-over-year increase in other operating expenses was driven primarily by the addition of public company costs, the development of the HLS team to support the Company's growth plans, an increase in patient support and regulatory compliance costs in the U.S. after a short-term decrease in cost a year earlier, and the costs associated with initial work to develop commercial plans for potential new cardiovascular product launches.

      Adjusted EBITDA

      The year-over-year change in Adjusted EBITDA is due to lower royalty revenue from Absorica and additional operating costs related to the expansion of the business, partially offset by the decrease in the cost of product sales and the year-to-date increase in Clozaril product sales. Adjusted EBITDA is a non-IFRS measure and is defined below.


      Three months ended December 31,

      Year ended December 31,


      2018

      2017

      2018

      2017






      Net income (loss) for the period

      369

      (421)

      (24,806)

      (6,097)

      Stock-based compensation

      537

      92

      1,062

      363

      Amortization and depreciation

      8,042

      8,136

      32,395

      32,233

      Acquisition and transaction costs

      143

      5

      891

      166

      Finance and related costs

      1,210

      5,558

      35,551

      24,264

      Provision for (recovery of) income taxes

      890

      2,091

      (3,997)

      4,952

      Adjusted EBITDA

      11,191

      15,461

      41,096

      55,881

      Interest Expense and Debt

      Interest on the senior secured term loan was $1.4 million in Q4 2018, compared to $4.2 million in Q4 2017. For the year-ended December 31, 2018, interest on the senior secured term loan was $12.2 million, compared to $16.6 million in 2017. The decrease in interest expense is primarily due to the Company's debt reduction and debt refinancing completed in August 2018. Following the debt refinancing, the Company expects to save up to $10.0 million per year in interest expense due to lower principal amount outstanding and the lower interest rate.

      As at December 31, 2018, the principal debt balance outstanding under the new senior secured term facility was $98.75 million compared to $100.0 million at September 30, 2018. This compares with the original senior secured loan borrowing of $185.0 million at the Company's inception and the $137.9 million original loan balance at the end of Q2 2018.

      Net Income (Loss)

      Net income in Q4 2018 was $0.4 million, or $0.01 per share, compared to a net loss of $(0.4) million, or $(0.02) per share in Q4 2017. For the year-ended December 31, 2018, net loss was $(24.8) million, or $(0.92) per share, compared to $(6.1) million, or $(0.24) per share, in 2017.

      Net loss in 2018 included $19.0 million of one-time costs related to the debt refinancing, of which $12.2 million was a non-cash charge to expense the remaining unamortized costs associated with the previous debt agreement.

      Cash from Operations and Financial Position

      Cash generated from operations was $11.2 million in Q4 2018, compared to $8.9 million in Q4 2017. Cash generated from operations for the year-ended December 31, 2018 was $32.7 million, compared to $27.2 million in 2017. The year-over-year increase is due to the debt refinancing in August 2018 and a reduction in working capital. 

      As at December 31, 2018, the Company had cash and cash equivalents of $10.9 million, compared to $36.2 million at December 31, 2017. The decrease in cash is primarily due to the use of surplus cash to reduce the loan principal outstanding. Accordingly, the loan principal outstanding decreased from $137.9 million at June 30, 2018 to $98.75 million at December 31, 2018.

      Q4 & FISCAL 2018 CONFERENCE CALL

      HLS will hold a conference call today at 8:30 am Eastern Time to discuss their Q4 and full-year 2018 financial results. The call will be hosted by Mr. Greg Gubitz, Chief Executive Officer, Mr. Gilbert Godin, President and Chief Operating Officer and Mr. Tim Hendrickson, Chief Financial Officer.

      DATE:

      Thursday, March 21, 2019

      TIME:

      8:30 am ET

      DIAL-IN NUMBER:

      (888) 231-8191 or (647) 427-7450

      WEBCAST LINK:

      https://event.on24.com/wcc/r/1933814/841BE360430C54EE39E4E3B19E0767E9  

      TAPED REPLAY:

      (855) 859-2056 or (416) 849-0833

      REPLAY PASSCODE:

      9374206

      A link to the live audio webcast of the conference call will also be available on the events page of the investors section of HLS Therapeutics' website at www.hlstherapeutics.com. Please connect at least 15 minutes prior to the conference call to ensure adequate time for any software download that may be required to hear the webcast. The taped replay will be available for 14 days and the archived webcast will be available for 90 days.

      ABOUT HLS THERAPEUTICS INC.

      Formed in 2015, HLS is a specialty pharmaceutical company focused on the acquisition and commercialization of late stage development, commercial stage promoted and established branded pharmaceutical products in the North American markets. HLS's focus is on products targeting the central nervous system and cardiovascular therapeutic areas. HLS's management team is composed of seasoned pharmaceutical executives with a strong track record of success in these therapeutic areas and at managing products in each of these lifecycle stages.

      CAUTIONARY NOTE REGARDING NON-IFRS MEASURES

      This press release refers to certain non-IFRS measures. These measures are not recognized measures under IFRS, do not have a standardized meaning prescribed by IFRS and are therefore unlikely to be comparable to similar measures presented by other companies. Rather, these measures are provided as additional information to complement those IFRS measures by providing further understanding of HLS's results of operations from management's perspective. Accordingly, they should not be considered in isolation nor as a substitute for analysis of HLS's financial information reported under IFRS. HLS uses non-IFRS measures to provide investors with supplemental measures of its operating performance and thus highlight trends in its core business that may not otherwise be apparent when relying solely on IFRS financial measures. HLS also believes that securities analysts, investors and other interested parties frequently use non-IFRS measures in the evaluation of issuers. HLS's management also uses non-IFRS measures in order to facilitate operating performance comparisons from period to period, prepare annual operating budgets and assess HLS's ability to meet its future debt service, capital expenditure and working capital requirements. 

      In particular, management uses Adjusted EBITDA as a measure of HLS's performance.  To reconcile net loss for the year with Adjusted EBITDA, each of (i) "stock-based compensation", (ii) "amortization and depreciation", (iii) "acquisition costs", (iv) "finance and related costs", and (v) "provision for (recovery of) income taxes" appearing in the Consolidated Statement of Net Loss are added to net loss for the year to determine Adjusted EBITDA. Adjusted EBITDA does not have any standardized meaning prescribed by IFRS and is not necessarily comparable to similar measures presented by other companies.  Adjusted EBITDA should not be considered in isolation or as a substitute for net income (loss) prepared in accordance with IFRS as issued by the IASB.

      FORWARD LOOKING INFORMATION

      This release includes forward-looking statements regarding HLS and its business. Such statements are based on the current expectations and views of future events of HLS's management. In some cases the forward-looking statements can be identified by words or phrases such as "may", "will", "expect", "plan", "anticipate", "intend", "potential", "estimate", "believe" or the negative of these terms, or other similar expressions intended to identify forward-looking statements, including, among others, statements with respect to HLS's pursuit of additional product and pipeline opportunities in certain therapeutic markets, statements regarding growth opportunities and expectations regarding financial performance. The forward-looking events and circumstances discussed in this release may not occur and could differ materially as a result of known and unknown risk factors and uncertainties affecting HLS, including risks relating to the specialty pharmaceutical industry, risks related to the regulatory approval process, economic factors and many other factors beyond the control of HLS. Forward-looking statements and information by their nature are based on assumptions and involve known and unknown risks, uncertainties and other factors which may cause HLS's actual results, performance or achievements, or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statement or information. Accordingly, readers should not place undue reliance on any forward-looking statements or information. A discussion of the material risks and assumptions associated with this release can be found in the Company's Annual Information Form dated October 26, 2018, which has been filed on SEDAR and can be accessed at www.sedar.com. Accordingly, readers should not place undue reliance on any forward-looking statements or information. Except as required by applicable securities laws, forward-looking statements speak only as of the date on which they are made and HLS undertakes no obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future events, or otherwise.

      HLS THERAPEUTICS INC.

      CONSOLIDATED STATEMENTS OF FINANCIAL POSITION

      [in thousands of U.S. dollars]






      As at

      As at



      December 31, 2018

      December 31, 2017





      ASSETS




      Current




      Cash and cash equivalents


      10,930

      36,219

      Accounts receivable


      17,569

      25,846

      Inventories


      1,505

      1,354

      Foreign currency forward contract


      755

      —

      Prepaid expenses and other current assets


      919

      1,617

      Total current assets


      31,618

      65,036

      Property, plant and equipment


      363

      441

      Intangible assets


      271,153

      312,659

      Restricted assets


      2,290

      5,555

      Deferred tax asset


      1,001

      955

      Total assets


      306,425

      384,646





      LIABILITIES AND SHAREHOLDERS' EQUITY

      Current




      Accounts payable and accrued liabilities


      12,405

      12,596

      Provisions


      6,574

      6,976

      Debt and other financial liabilities


      18,920

      14,160

      Income taxes payable


      369

      870

      Total current liabilities


      38,268

      34,602

      Debt and other financial liabilities


      104,459

      158,114

      Deferred tax liability


      5,209

      11,548

      Total liabilities


      147,936

      204,264





      Shareholders' equity




      Share capital


      210,360

      192,743

      Contributed surplus


      12,973

      12,330

      Accumulated other comprehensive income (loss)


      (7,455)

      5,941

      Deficit


      (57,389)

      (30,632)

      Total shareholders' equity


      158,489

      180,382

      Total liabilities and shareholders' equity

      306,425

      384,646

      HLS THERAPEUTICS INC.

      CONSOLIDATED STATEMENTS OF NET INCOME (LOSS)

      [in thousands of U.S. dollars, except per share amounts]


      Three months ended December 31,

      Year ended December 31,



      2018

      2017

      2018

      2017







      Revenue


      16,661

      20,375

      61,415

      75,082







      Expenses






      Cost of product sales


      592

      633

      2,595

      4,136

      Selling and marketing


      1,380

      1,137

      4,323

      3,551

      Medical, regulatory and patient support


      1,153

      1,393

      4,437

      3,875

      General and administrative


      2,345

      1,751

      8,964

      7,639

      Stock-based compensation


      537

      92

      1,062

      363

      Amortization and depreciation


      8,042

      8,136

      32,395

      32,233

      Operating income


      2,612

      7,233

      7,639

      23,285

      Acquisition and transaction costs


      143

      5

      891

      166

      Finance and related costs, net


      1,210

      5,558

      35,551

      24,264

      Loss before income taxes


      1,259

      1,670

      (28,803)

      (1,145)

      Income tax expense (recovery)


      890

      2,091

      (3,997)

      4,952

      Net income (loss) for the period


      369

      (421)

      (24,806)

      (6,097)





      Net loss per share:




      Basic and diluted


      $0.01

      $(0.02)

      $(0.92)

      $(0.24)

      HLS THERAPEUTICS INC.

      CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS)

      [in thousands of U.S. dollars]




      Three months ended December 31,

      Year ended December 31,


      2018

      2017

      2018

      2017






      Net income (loss) for the period

      369

      (421)

      (24,806)

      (6,097)






      Item that may be reclassified subsequently to





      net income (loss)





      Unrealized foreign currency translation





      adjustment

      (7,978)

      (403)

      (13,396)

      10,552

      Comprehensive income (loss) for the period

      (7,609)

      (824)

      (38,202)

      4,455

      HLS THERAPEUTICS INC.

      CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS' EQUITY

      [in thousands of U.S. dollars]








      Share

      capital

      Contributed

      surplus

      Accumulated
      other
      comprehensive
      income (loss)

      Deficit

      Total








      Balance, December 31, 2016


      192,743

      11,967

      (4,611)

      (24,535)

      175,564

      Stock option expense


      —

      363

      —

      —

      363

      Net loss for the year


      —

      —

      —

      (6,097)

      (6,097)

      Unrealized foreign currency

      translation adjustment








      —

      —

      10,552

      —

      10,552

      Balance, December 31, 2017


      192,743

      12,330

      5,941

      (30,632)

      180,382

      Common shares issued


      19,905

      —

      —

      —

      19,905

      Share issuance costs


      (1,252)

      —

      —

      —

      (1,252)

      Shares repurchased


      (1,036)

      —

      —

      112

      (924)

      Stock option expense


      —

      643

      —

      —

      643

      Net loss for the year


      —

      —

      —

      (24,806)

      (24,806)

      Dividends declared


      —

      —

      —

      (2,063)

      (2,063)

      Unrealized foreign currency


      —

      —

      (13,396)

      —

      (13,396)

      translation adjustment

      Balance, December 31, 2018


      210,360

      12,973

      (7,455)

      (57,389)

      158,489

      HLS THERAPEUTICS INC.

      CONSOLIDATED STATEMENTS OF CASH FLOWS

      [in thousands of U.S. dollars]




      Three months ended
      December 31,

      Year ended December 31,


      2018

      2017

      2018

      2017






      OPERATING ACTIVITIES





      Net income (loss) for the period

      369

      (421)

      (24,806)

      (6,097)

      Adjustments to reconcile net income (loss) to cash provided by





      operating activities

      Stock option expense

      248

      92

      643

      363

      Amortization and depreciation

      8,042

      8,136

      32,395

      32,233

      Debt refinancing costs

      —

      —

      18,951

      —

      Accreted interest

      613

      1,656

      4,895

      6,770

      Fair value adjustment on financial assets and liabilities

      (635)

      (409)

      (775)

      770

      Listing expense

      —

      —

      435

      —

      Deferred income taxes

      251

      1,103

      (5,446)

      1,570

      Net change in non-cash working capital balances related to

      2,268

      (1,260)

      6,455

      (8,443)

      operations

      Cash provided by operating activities

      11,156

      8,897

      32,747

      27,166






      INVESTING ACTIVITIES





      Additions to property, plant and equipment

      (7)

      (129)

      (99)

      (179)

      Acquisitions

      (4,325)

      (1,825)

      (13,800)

      (9,800)

      Other additions to intangible assets

      (363)

      (209)

      (682)

      (554)

      Cash used in investing activities

      (4,695)

      (2,163)

      (14,581)

      (10,533)






      FINANCING ACTIVITIES





      Common shares issued

      —

      —

      19,470

      —

      Common share issuance costs

      —

      —

      (1,699)

      —

      Common shares repurchased

      —

      —

      (924)

      —

      Dividends paid

      (1,047)

      —

      (1,047)

      —

      Repayment of original senior secured term loan


      (4,550)

      (151,271)

      (13,132)

      Drawdown of new senior secured loan

      —

      —

      100,000

      —

      Repayment of new senior secured term loan

      (1,250)

      —

      (1,250)

      —

      Cash portion of debt refinancing costs

      (3,000)

      —

      (11,453)

      —

      Decrease (increase) in restricted cash

      —

      (1,500)

      5,555

      (4,600)

      Lender royalty payment

      —

      (121)

      (237)

      (478)

      Cash used in financing activities

      (5,297)

      (6,171)

      (42,856)

      (18,210)






      Net increase (decrease) in cash and cash equivalents

      1,164

      563

      (24,690)

      (1,577)

      Foreign exchange on cash and cash equivalents

      (141)

      (56)

      (599)

      33

      Cash and cash equivalents, beginning of period

      9,907

      35,712

      36,219

      37,763

      Cash and cash equivalents, end of period

      10,930

      36,219

      10,930

      36,219

      SOURCE HLS Therapeutics Inc.

      Dave Mason, Investor Relations, HLS Therapeutics Inc., (416) 247-9652, [email protected]; Gilbert Godin, President and Chief Operating Officer, HLS Therapeutics Inc., (484) 232-3400 ext101, [email protected]

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      HLS Therapeutics Inc.

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