Which embryos have the best opportunity to develop into a viable
pregnancy? A new technology provides a surprising answer.
AARHUS, Denmark, Sept. 18, 2012 /CNW/ - A major challenge in the field
of IVF is selecting the single best embryo which is likely to result in
a live birth. Currently, embryologists must remove the embryo from a
standard incubator to perform 2 or 3 short evaluations of the
developing embryo under the microscope, at fixed time-points over 3-5
days, in order to assess embryo quality prior to transferring an embryo
to the patient.
The EmbryoScope® Time-lapse system generates a movie allowing embryologists to monitor
various characteristics of the embryo development over the entire
incubation period, while maintaining optimum incubation conditions in a
According to breakthrough scientific results, embryos which exhibit
irregular division patterns have a much lower pregnancy potential. The
results were made available online on August 27 in the journal Fertility & Sterility, and confirms the benefits of implementing the EmbryoScope® Time-lapse system from the Danish company Unisense FertiliTech A/S.
A clinical multi-center study from Equipo IVI, Spain, Maigaard clinic
and Brædstrup Hospital in Denmark, including a total of 5225 embryos,
reports significantly reduced implantation of embryos which have a
second division cycle occurring in less than 5 hours (considered direct
cleavage), compared to the implantation probability of "normally"
developing embryos. The embryos with a short second division cycle will
simply not have enough time for DNA replication, which is a
prerequisite for a normal cell division.
Nearly 14% of all examined embryos exhibited this division pattern and
according to the study will have a greatly reduced probability of
resulting in a viable pregnancy. For both patients and fertility
clinics it is important to decrease transfer of embryos with low very
low implantation potential. With this new technology, clinics now have
objective criteria with which to identify the embryo with a higher
chance of implanting allowing more successful single embryo transfer
Marcos Meseguer, co-author of the paper and senior embryologist at
Equipo IVI in Valencia, states "The ability to identify abnormal
development events in embryos is certainly a key advantage of using
time-lapse systems such as the Embryoscope® allowing us to improve our patient treatment".
The improvement potential of implementing time-lapse systems is
increasing constantly as scientists discover new information about
early human embryo development and more than 180 IVF clinics are using
the Embryoscope® technology worldwide.
About Unisense FertiliTech A/S:
Unisense FertiliTech A/S was founded in 2003 to develop technology to
improve human embryo assessment in assisted reproduction. Unisense
FertiliTech has developed, and manufactures the EmbryoScope®- a unique Time-lapse system facilitating improved IVF treatment,
flexible work routines and effective communication through
comprehensive documentation of embryo development and evolving
improvements in selection. The System is FDA 510(k) cleared and CE marked as a Class II medical
Our Mission is to help infertile couples achieve their dream of
parenthood through development of novel technology, quantification and
digitized documentation. "The Vision to Conceive"
SOURCE: Unisense FertiliTech A/S
For further information:
CEO, Jens Gundersen
COO, Søren Ankerstjerne
Unisense FertiliTech A/S