Ontario Government Lists Prolia on Public Drug Plans
TORONTO, Feb. 29, 2012 /CNW/ - Osteoporosis Canada congratulates the
Ontario government for providing access to a therapy in a new class of
osteoporosis medications. Prolia® (denosumab) is now available on
public and private drug plans in Ontario, meaning women with
postmenopausal osteoporosis at high risk for fractures have access to
increased treatment options.
"With the announcement of Prolia available on public and private drug
plans in Ontario, women with osteoporosis in Ontario will have access
to novel therapeutic options for the treatment of this debilitating
disease," said Dr. Famida Jiwa, president and CEO, Osteoporosis Canada.
"While Osteoporosis Canada applauds the Ontario government for
increasing access, the organization continues to work with other
provinces and territories to ensure that all patients with osteoporosis
have options and access to the medications they need."
"The listing of denosumab on drug plans means that physicians in Ontario
are better able to manage this disease in postmenopausal women at high
risk of fracture as they have increased options for treatment," said
Dr. Bill Leslie, Chair, Scientific Advisory Council, Osteoporosis
Canada. "In the end what's imperative is that women with osteoporosis
are able to access all medications to treat this debilitating disease."
Ontario Government Criteria for Denosumab
All women in Ontario covered by the provincial drug plan or by private
drug plans now have access to denosumab, a new treatment for
postmenopausal women with osteoporosis at high risk for fracture.
Denosumab is recommended for women with postmenopausal osteoporosis who
A) have experienced a further significant decline in bone mineral
density (BMD) after one year of continuous bisphosphonate therapy, or
B) would otherwise be eligible for jurisdictional funding for oral
bisphosphonates, but for whom bisphosphonates are contraindicated due
to hypersensitivity or abnormalities of the esophagus (e.g., esophageal
stricture or achalasia). In both cases, women must also meet at least
two of the following criteria: be older than 75 years; experienced a
prior fragility fracture; or have a BMD T-score of ≤-2.5.
"If you have a debilitating disease, such as osteoporosis, it is
critical to be able to access all medications that can help to improve
your health and well being," said Larry Funnell, chair, Canadian
Osteoporosis Patient Network (COPN).
Osteoporosis could strike you or someone you love. It is a silent
disease that affects nearly two million Canadians. The risk of a major
osteoporotic fracture in Canada is among the highest in the world. Yet,
despite the high prevalence of fractures, they are often not
appropriately assessed or treated, leaving osteoporosis undiagnosed and
undertreated. Broken bones are associated with devastating health
consequences including pain, decreased quality of life, loss of
independence, and even death. Preventing new fractures for those who
have already had an osteoporotic fracture is Osteoporosis Canada's top
priority. In 2010, Osteoporosis Canada issued new Clinical Practice
Guidelines for the Diagnosis and Management of Osteoporosis in Canada1 that help physicians and patients better identify the risk of fracture,
resulting in better fracture prevention and better management of
Additional osteoporosis statistics:
Almost two million Canadians are living with osteoporosis.
More than 90 per cent of hip fractures in Canada occur in those over age
In the first year after a vertebral or hip fracture, there is at least a
doubling in the risk of death.
There are about 30,000 hip fractures each year in Canada; many more
Canadians suffer osteoporotic fractures affecting the spine, wrist,
shoulder, and pelvis.
A 50-year-old woman has a 40 per cent chance of developing a hip,
vertebral or wrist fracture during her lifetime.2
More than one quarter of hip fractures in Canada occur in men.
The one-in-six lifetime risk of hip fracture is greater than the
one-in-nine lifetime risk of developing breast cancer.3
One in four women who have a new vertebral fracture will fracture again
within one year.4
About Osteoporosis Canada
Osteoporosis Canada, a registered charity, is the only national
organization serving people who have or are at risk for osteoporosis.
In keeping with its vision of a Canada without osteoporotic fractures,
the organization works to educate, empower and support individuals and
communities in the risk-reduction and treatment of osteoporosis by
providing medically accurate information to patients, health
professionals and the public. For more information, visit www.osteoporosis.ca.
1 Papaioannou A et al. Clinical practice guidelines for the diagnosis and
management of osteoporosis in Canada. CMAJ. 2010; 1-10.
2 Melton LJ III, Chrischilles EA, Cooper C, Lane AW, Riggs BL.
Perspective: how many women have osteoporosis? J Bone Miner Res. 1992; 7:1005-10.
3 Cummings SR, Black DM, Rubin SM. Lifetime risks of hip, colles', or
vertebral fracture and coronary heart disease among white
postmenopausal women. Arch Intern Med. 1989; 149:2445-8.
4 Lindsay R, Burge RT, Strauss DM. One year outcomes and costs following
a vertebral fracture. Osteoporosis Int. 2005; 16:78-85.
SOURCE Osteoporosis Canada
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