Promising new breast cancer therapy receives $1M boost from Breast
Cancer Society of Canada
SARNIA, ON, July 4, 2012 /CNW/ - Future breast cancer patients facing a
difficult-to-treat form of the disease may have new hope in an
innovative treatment being devised by researchers at Sunnybrook Health
Sciences Centre in Toronto.
A team of experts from Sunnybrook's Odette Cancer Centre - with a
$1-million boost from the Breast Cancer Society of Canada - is studying
how combining microbubbles and ultrasound in pre-clinical models can
make locally advanced breast tumours more responsive to chemotherapy
and radiation treatments.
Locally advanced breast cancer is an aggressive form of the disease that
is resistant to treatment and has an extremely high mortality rate
within two years of diagnosis. These tumours, typically found in women
between ages 35 and 45, are five centimetres or larger and grow at an
Sunnybrook research has found that the tiny microbubbles begin to bounce
and expand when heated with focused ultrasound, straining the blood
vessels of the tumour. The cancer cells become leaky and weak. When a
tumour is targeted in this manner prior to radiation in pre-clinical
models, there is significant enhancement of the radiation effect and
"The $1-million boost from the Breast Cancer Society of Canada is going
to allow us to scale up these treatments and move them out of the
laboratory and into breast cancer patients in the next three to five
years," says Dr. Greg Czarnota, radiation oncologist and lead on this
research. "This is definitely a world first happening at Sunnybrook."
"The Breast Cancer Society of Canada is dedicated to supporting medical
breakthroughs that can have an impact on patient care," said Marsha
Davidson, Executive Director, Breast Cancer Society of Canada. "That's
why we've chosen to support Dr. Czarnota's research - the speed and
success of this therapy could dramatically improve therapy for women
with locally advanced breast cancer."
Dr. Jon S. Dellandrea, president and CEO of Sunnybrook Foundation, said
the gift is an excellent example of the innovations in treatment made
possible through donor support.
"We are extremely grateful for this investment from the Breast Cancer
Society of Canada," said Dr. Dellandrea. "Sunnybrook's goal is to
invent the future of health care, and this type of visionary support is
essential if we're to conduct the research, develop the treatments, and
provide the care necessary to realize that goal."
The Breast Cancer Society of Canada's mandate is to donate funds for two
specific kinds of research: seed funding for basic research, and
project-based funding for translational research. Translational
research helps turn new discoveries into new approaches to patient care
as quickly as possible.
The Breast Cancer Society of Canada has been supporting breast cancer
research at Sunnybrook for three years, and has donated more than $1.2
About the Breast Cancer Society of Canada
The Breast Cancer Society of Canada is a registered, national, not-for-profit, charitable organization
dedicated to funding Canadian breast cancer research into the
detection, prevention, treatment and to ultimately find a cure for the
disease that women fear most. For more information please visit www.bcsc.ca.
About Sunnybrook Health Sciences Centre
Sunnybrook is an internationally recognized leader in research and
education, and is fully affiliated with the University of Toronto.
Sunnybrook specializes in caring for Canada's war veterans, high-risk
pregnancies, critically ill newborns, adults and the elderly, and
treating and preventing cancer, cardiovascular disease, neurological
and psychiatric disorders, orthopedic disorders and traumatic injuries.
For more information about how Sunnybrook is inventing the future of
health care, please visit www.sunnybrook.ca
SOURCE Breast Cancer Society of Canada
For further information:
Sunnybrook Health Sciences Centre
Direct: 416-480-6150 ext. 2250