Siemens Medical Solutions Diagnostics Inks Agreement with KreLo Medical Diagnostics to Expand Thyroid Immunoassay Menu

    Third-Generation TRAb Assay Delivers Unprecedented Specificity for
    Diagnosing Graves' Disease

    DEERFIELD, Ill., Dec. 17 /CNW/ -- Siemens Medical Solutions Diagnostics
( announced that it has signed an agreement with
KreLo GmbH Medical Diagnostics for the rights to develop an automated
stimulating TSH receptor antibody (TRAb) assay used in the differential
diagnosis of Graves' disease. This agreement will make Siemens Medical
Solutions Diagnostics the first in vitro diagnostics distributor of an
automated TRAb assay featuring stimulating TRAb KreLo antibodies which are
specific to the diagnosis of Graves' disease.

    (Logo: )

    "The new TRAb assay has enormous potential to help diagnose, monitor and
predict the course of Graves' disease," said Joe Bernardo, senior vice
president, Central Lab Testing, Siemens Medical Solutions Diagnostics.
"Siemens continues to focus on new biomarker development opportunities,
continually expanding our already comprehensive immunoassay menu and providing
the diagnostic tools necessary to diagnose and treat millions of thyroid
disease patients."
    Graves' disease affects approximately 32 million people worldwide. As one
of the most common form of hyperthyroidism, Graves' is an autoimmune disorder
characterized by the presence of stimulating TSH receptor autoantibodies found
approximately 90 percent of Graves' patients. TSH receptor autoantibodies
mimic the activity of TSH, leading to an elevated production of thyroid
hormone. Left untreated, Graves' disease can lead to miscarriage, birth
defects, thyroid eye disease and can be life-threatening.
    Studies have shown that the TRAb test has the highest diagnostic power to
differentiate Graves' disease from toxic nodular goiters.  KreLo GmbH focuses
on research and development of diagnostic kits for application in human
medicine. It was co-founded by Werner Kress and Prof. Ulrich Loos, formerly
professor at the Department of Medicine at Ulm University (Ulm, Germany).
Prof. Loos is the CEO of KreLo GmbH.

    About Siemens Medical Solutions Diagnostics

    Siemens Medical Solutions Diagnostics is the leading clinical diagnostics
provider in the world. The company offers health care professionals the
broadest range of diagnostic products and services that are used for
diagnosing medical conditions, monitoring patient therapy and providing
quality health care. Siemens' comprehensive portfolio of solutions and highly
responsive service are designed to improve clinical outcomes, streamline
workflow and enhance the operational efficiency of clinical laboratories
around the world. Visit

    About Siemens Medical Solutions

    Siemens Medical Solutions is one of the world's largest suppliers to the
healthcare industry. The company is a renowned medical solutions provider with
core competence and innovative strength in diagnostic and therapeutic
technologies as well as in knowledge engineering, including information
technology and system integration. With its laboratory diagnostics
acquisitions, Siemens Medical Solutions will be the first fully integrated
diagnostics company, bringing together imaging and lab diagnostics, therapy,
and healthcare information technology solutions, supplemented by consulting
and support services. The company delivers solutions across the entire
continuum of care -- from prevention and early detection, to diagnosis,
therapy and care. Siemens Medical Solutions employs more than 49,000 people
worldwide and operates in 130 countries. According to IFRS, in the fiscal year
2007 (Sept. 30), Siemens Medical Solutions reported sales of euro 9.85
billion, orders of euro 10.27 billion, and group profit of euro 1.32 billion
(preliminary figures, unaudited). Further information can be found by visiting

For further information:

For further information: Amanda Naiman of Siemens Medical Solutions 
Diagnostics, +1-610-448-4531, Web Site:,

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