Next Safety Announces Stunning Advance in Nicotine Delivery



    Conclusive test results prove pulmonary device provides far higher
efficacy than cigarettes

    JEFFERSON, N.C., August 13 /CNW/ - In a study of 30 test subjects,
participants achieved much higher nicotine blood levels at faster rates than
those possible from smoking cigarettes, without receiving any of the deadly
carcinogens. Each subject inhaled less nicotine than typically inhaled from
smoking one cigarette: with greater psychoactive effects.

    According to an article published by the World Health Organization,
cigarettes, which are more addictive than cocaine, will kill more than 600
million people over the next thirty years.

    "Our country is intellectually dishonest, when we allow the executives
from major tobacco companies to live "the country club lifestyle," while
intentionally shipping products that are more addictive than cocaine, killing
millions of people every year; at the same time, we imprison hundreds of
thousands of the poor for selling marijuana," said C. Eric Hunter, CEO. The
nine-year-old son of Mr. Hunter, poignantly asked a Next Safety colleague, in
a discussion of cigarette addiction, "Why do people kill other people just for
money."

    Next Safety's revolutionary new device, with advanced dosing controls,
allows those addicted to tobacco a mechanism to receive nicotine with the same
psycho active effects achieved by smoking cigarettes, without inhaling the
known carcinogens contained in cigarettes. The high degree of control allows
the device to be used for smoking cessation by slowly decreasing inhaled
nicotine over long periods of time or for nicotine replacement, where people
are unable to stop using inhaled nicotine. Additional immediate benefits
include the elimination of second hand smoke and other negative secondary
effects.

    In this study smokers achieved mean nicotine venous blood level increases
of 28.4 nanograms per milliliter less than ten seconds after inhalation.
Nonsmokers do not have the same diffusion barrier caused by the inhalation and
subsequent deposition of cigarette combustion byproducts in the lungs, which
smokers have. Therefore, nonsmokers achieved nicotine blood levels of 129
nanograms per milliliter in less than ten seconds after inhalation (laboratory
analysis performed by NMS Labs).

    This breakthrough in pulmonary drug delivery is not limited to only
nicotine. Any drug soluble in water can now be delivered with very high
efficacy and efficiency utilizing Next Safety's proprietary pulmonary devices
and methods. Treatments enabled by the technology include the efficient and
high efficacy delivery of numerous drugs never before effectively delivered
through pulmonary means. For example, in the announced nicotine results, more
than 74 percent of the nicotine contained in the device entered the blood
stream. Many drugs currently delivered only through IV or injection in
important classes such as antibiotics, analgesics and anti medics along with
certain vaccinations can now be delivered with very high precision, efficacy
and efficiency.

    Next Safety moved into a new 32,000 square ft. facility on July 27th.
During the following eighteen months the company expects to occupy 850,000
square feet of additional office/manufacturing space and hire approximately
3,600 employees.

    Next Safety's nicotine delivery device will be priced at less than
$100.00, with refills costing less than ten percent of the average pack of
cigarettes in developed countries on a nicotine equivalent basis. The company
will begin shipping devices to markets where current regulations allow in
December. Next Safety will ship more than two million nicotine delivery
devices per month during the first quarter of 2008.

    The company will begin sampling devices to certain reporters in Boston on
Wednesday, August 15th, on Thursday, August 16th and in New York on Monday,
August 20th. In addition, the company will hold a moderated discussion at the
Mandarin Oriental in New York on Tuesday, August 21st. Attendees will include:
leading pulmonologists, reporters and public officials, as well as smokers and
non-smokers. For more information on the August 21st event or for an
invitation, please call or write Christy Cheek at 336.246.7700 ext.230 or
christycheek@nextsafetyinc.com.

    MULTIMEDIA AVAILABLE:
http://www.businesswire.com/cgi-bin/mmg.cgi?eid=5470111




For further information:

For further information: Next Safety Christy Cheek, 336-246-7700 ext.
230 christycheek@nextsafetyinc.com

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