Masters Group Granted Global Distribution Rights to New Break-Through Melatonin Based Sleep Aid

    MIAMI, June 5 /CNW/ - The Masters Group is pleased to announce that it
has been granted exclusive worldwide distribution rights to Mellow-Tone(TM). 
Mellow-Tone(TM) is a break-through premium dietary supplement made from
pharmaceutical grade Melatonin.  It is intended for use by persons suffering
from occasional insomnia or sleep difficulty caused by restlessness, nervous
tension, anxiety, mild to moderate mood changes, and jet lag as well as
daytime drowsiness caused by occasional sleeplessness.
    Sleep researchers estimate that occasional insomnia affects over 37
million people in the U.S. and conservatively place the number of people
suffering from the condition worldwide at well over 100 million people.  The
prevalence of this sleep disorder globally is expected to increase
dramatically over the next few years.  The current market is valued at USD
$4.3 billion but is forecast to increase by 158% to USD $11 billion by 2012.
    Sleep deprivation results in a wide variety of negative health and
economic consequences.  In the short term, lack of sleep can impair our
ability to perform routine daily activities.  It affects us both mentally and
physically.  These effects include fatigue, irritability, careless mistakes,
difficulty concentrating, slower reaction times, and increased stress.
Prolonged sleep deprivation can also lead to very serious long-term health
problems including an increased risk of hypertension, diabetes, obesity,
depression, heart attack, and stroke.  The economic impact of sleep
deprivation on a societal basis is staggering.  Estimates of the direct and
indirect financial costs of sleeplessness are in the hundreds of billion of
dollars annually.  Direct costs are those incurred for the actual medical
treatment of sleep disorders, and indirect costs are those that are linked to
peoples' sleeplessness such as reduced productivity and property damage.
    There is hope in addressing this looming public health crisis.  Clinical
studies show that the hormone Melatonin administered as a dietary supplement
is effective in increasing the overall quantity and quality of one's sleep.
Melatonin is an essential physiological agent that is produced in the brain by
the pineal gland to regulate Circadian rhythms as well as other bodily
systems.  Circadian rhythms are regular changes in mental and physical
characteristics that take place naturally in the course of a day.  Among these
natural daily rhythms is an increase in the level of Melatonin at night,
making people feel drowsy.  Recent research has linked numerous health
problems to dysfunctions of Circadian rhythms including various sleep
    In a review of 28 clinical trials involving Melatonin on behalf of the
U.S. Department of Health and Human Services, researchers found that the
results were clinically and statistically significant based on sleep
efficiency criteria, which is a comparison of the amount of time participants
spent asleep to the total time spent in bed.  In another systematic analysis
of 33 clinical trials, researchers found that the use of Melatonin resulted in
a clinically and statistically significant reduction in the onset of sleep. In
addition, study participants given Melatonin spent more time in REM sleep,
woke up less often, and reported improved sleep quality compared with those
study participants given a placebo.  The results of the clinical studies
reviewed clearly indicate that Melatonin taken as a dietary supplement is
effective in improving the overall quality and quantity of sleep.
    Mellow-Tone(TM) offers a unique sublingual delivery system in a strip
placed on the tongue.  It is doctor formulated and doctor recommended and is
available through physician offices and other healthcare providers.  Mellow-
Tone(TM) is manufactured in the United States by KRS Global Biotechnology,
    The Masters Group is a premier customer-focused, full-service wholesale
distribution company that ethically markets and distributes prescription and
OTC pharmaceuticals, medical supplies, and equipment to the global healthcare
community.  The Masters Group has offices in the United States, England, and
El Salvador.  We proudly serve the local and national medical needs of clients
located on nearly every continent, focusing specifically on niche markets in
the United States, Latin America, the Caribbean, Europe, the Middle East,
Africa, and Asia.  For more information about The Masters Group, kindly visit
us at

For further information:

For further information: Ms. Shawn Resch, C.E.O. of Masters Medical
Inc., +1-954-474-2210, Fax, +1-954-474-1395,

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