Don't Leave Your Vision to Chance on World Glaucoma Day

    - Leading Glaucoma Experts Act to Help Prevent Vision Loss as 50 Percent
    of Patients Remain Undiagnosed

    LONDON, March 5 /CNW/ - On the first World Glaucoma Day (March 6, 2008),
leading glaucoma experts globally are asking those who may be at risk of the
condition not to leave their vision to chance - with a clear message that 50
percent of people with open-angle glaucoma and more than 50 percent of people
with angle-closure glaucoma are unaware they have it.(1),(2) In addition, 50
percent remain untreated until a large amount of irreversible vision loss has
already occurred.(1)
    During World Glaucoma Day, experts are encouraging patients at risk for
glaucoma to utilize resources from sources like the All Eyes on Glaucoma(TM)
campaign, which aims to help people recognize and understand the devastating
consequences of glaucoma - the world's second leading cause of blindness. The
All Eyes on Glaucoma campaign also seeks to increase public awareness of risk
factors for glaucoma and reinforce the critical importance of having regular,
complete eye examinations. One key component of the campaign is the
interactive consumer website,, which offers
tools such as an "Am I at Risk" quiz and a "Conversation Starter" on important
questions to ask at the eye doctor.
    World Glaucoma Day is a joint initiative by the World Glaucoma  
Association (WGA) and World Glaucoma Patient Association (WGPA) designed to   
promote awareness of eye health and the importance of regular eye   
examinations to reduce the onset of glaucoma. Due to the rapidly growing 
aging population, the prevalence of glaucoma is expected to rise from 60  
million in 2010 to 80 million in 2020 globally.(3)
    "World Glaucoma Day offers an opportunity to send a clear message about  
 preventing glaucoma and helping preserve vision - although glaucoma may   
affect all age groups, individuals at risk and those over age 40 should have  
   regular, comprehensive eye exams that include careful evaluation of the  
optic nerve and measurement of eye pressure," said Dr. Robert Weinreb,
President of the American Glaucoma Society, Past President of the WGA and
Distinguished Professor of Ophthalmology at the University of California, San
Diego, USA. "Since vision loss from glaucoma is permanent, glaucoma needs to
be diagnosed and treated as early as possible."

    Important Steps to Proactively Protect Your Vision

    Step 1: Learn the Risk Factors

    Since glaucoma may not have any early symptoms, the first step in    
preventing glaucoma is to learn the risk factors and to discuss them with an  
  eye health professional. The primary risk factors for glaucoma include:(4)

    - Increasing age

    - High eye pressure (or intraocular pressure/IOP)

    - Family history of glaucoma

    - African and Chinese ancestry(5)

    - Nearsightedness

    - High blood pressure(6)

    Step 2: Get a Complete Eye Examination

    For all individuals, especially those at high risk of developing and   
losing sight from glaucoma, the World Glaucoma Association recommends    
getting a regular, complete eye exam that includes tests that measure eye
pressure, assess the optic nerve and test visual field, including the

    - Tonometry: Measures eye pressure which should be tracked over time

    - Optic nerve exam: Evaluates the optic nerve structure

    - Visual Field test: Visual field (or peripheral or side vision)
      measures the entire area you can see while looking at a fixed point

    Impact of Functional Vision Loss

    The consequences of vision loss due to irreversible optic nerve damage   
 can greatly affect one's independence, such as the ability to drive and    
perform basic daily activities due to sensitivity to light, problems with    
glare, blurred vision and trouble seeing in dark places. According to the    
American Journal of Ophthalmology, quality of life is also greatly affected.
    In fact, nearly 35 percent of newly diagnosed glaucoma patients reported 
   symptoms of nervousness, anxiety or stress.(7)
    "In addition to a greater risk of disability, delayed diagnosis of   
glaucoma results in increased healthcare costs for both the individual and   
society as a whole," said Professor Roger Hitchings, Professor of   
Ophthalmology, University College London and Consultant Ophthalmic Surgeon,   
 Moorfields Eye Hospital, London, England. "It is crucial to elevate the  
importance of eye health now to reduce the burden of functional vision loss   
later as the aging population continues to grow."

    About All Eyes on Glaucoma

    The campaign All Eyes on Glaucoma(TM) is sponsored by Pfizer Ophthalmics 
  and encourages at-risk individuals to understand more about glaucoma and the
    practical steps that need to be taken to preserve eye health and prevent  
 optic nerve damage. The global educational program offers an informative    
website,, that provides online resources   
and support to help people take action now and avoid the negative consequences
of vision loss later.

    About Pfizer Ophthalmics

    Pfizer Ophthalmics, a division of Pfizer Inc, is committed to preserving 
  sight and eliminating preventable blindness. Pfizer Ophthalmics discovers,  
 develops and provides leading treatments in ophthalmology to support patients
   who are at risk of blindness or suffering from vision impairment, and to   
 serve the health care professionals who treat them. Its current product line 
   includes the most prescribed treatment to lower elevated eye pressure in   
 patients with ocular hypertension (abnormally high eye pressure) or
open-angle glaucoma. Pfizer Ophthalmics also markets a treatment for
neovascular age related macular degeneration outside the U.S. This same
treatment is marketed in the U.S. by (OSI) Eyetech.

    Notes to Editors:

    Glaucoma is the name given to a series of devastating diseases that  
irreversibly damage the eye's optic nerve. If left unchecked, this can result
in serious vision loss over time. Glaucoma is commonly detected by measuring
the pressure in the eye, also known as intraocular pressure (IOP). When eye
pressure increases over time, the optic nerve becomes damaged. Worldwide, an
estimated 6.7 million people are blind from glaucoma, with approximately 70
million people living with the condition.(8)

    The two most common forms of glaucoma are:

    - Open-angle glaucoma - when the pressure in the eye increases over time
      due to poor drainage of the aqueous humor.

    - Angle-closure glaucoma - when the iris is too close to the drainage
      canal (trabecular meshwork).

    The only modifiable glaucoma risk factor is high eye pressure, though it 
  is possible to develop the condition without it. Due to the build-up of  
natural fluid produced by the eye, high eye pressure causes permanent damage  
  to the optic nerve, the "cable" used by the eye to communicate to the brain.
   High eye pressure may exist without noticeable symptoms so many people do
not     know they have it if their vision is not checked regularly. In fact,
people may not notice vision loss until 40 percent or more of their optic
nerve has been damaged.(9) IOP is an easily identifiable risk factor; however
people who fall within the normal IOP range may still be at risk for glaucoma.

    (1) World Health Organization. Bulletin of the World Health
        Organization. In Focus. Nov 1, 2004. Available at: Accessed
        July 16, 2007.

    (2) Thomas R, Sekhar GC, Parikh R. Primary angle closure glaucoma: a
        developing a world perspective. Clinical & Experimental Ophthalmology
        2007; 35(4): 374-378(5)

    (3) Quigley HA, Broman AT. The number of people with glaucoma worldwide
        in 2010 and 2020. Br J Ophthalmol. 2006; 90: 262-267.

    (4) The Glaucoma Foundation. Who's At Risk? Available at: Accessed on August 24,

    (5) World Health Organization. Bulletin of the World Health
        Organization. In Focus, Nov. 1 2004

    (6) U.S. Food and Drug Administration. Guarding Against Glaucoma.
        Available at:
        Accessed on August 24, 2007

    (7) Jampel HD, Frick KD, Janz NK. Depression and Mood Indicators in
        Newly Diagnosed Glaucoma Patients. American Journal of Ophthalmology.
        2007; 144(2): 238-244.e1.

    (8) Congdon NG, Friedman DS, Lietman T. Important Causes of Visual
        Impairment in the World Today. JAMA. 2003; 290: 2057-2060.

    (9) American Family Physician. Open-Angle Glaucoma - May 1, 2003.
        Available at: Accessed
        August 8, 2007.

For further information:

For further information: Con Franklin: +44-20-711311313,

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