Cangene's anthrax immune globulin delivered and accepted into U.S. Strategic National Stockpile



    Listed TSX, Symbol: CNJ

    TORONTO and WINNIPEG, Aug. 29 /CNW/ - Cangene Corporation today reports
that it has completed delivery of the initial order for anthrax immune
globulin and the drug has been formally received into the U.S. Strategic
National Stockpile ("SNS"). This acceptance of product into the SNS by the
U.S. Department of Health and Human Services (managed by the U.S. Biomedical
Advanced Research and Development Authority ("BARDA") within HHS) confirms
that Cangene can proceed to invoice for approximately one third of the
previously disclosed $US18-22 million total; the remainder will be invoiced
shortly, when delivery of the botulism toxin immune globulin has similarly
been completed.
    "Although the important step was meeting the regulatory and manufacturing
criteria required under the contract, this delivery triggers a significant
payment. Operationally and financially, we're pleased to finalize this
delivery," said Dr. John Langstaff, Cangene's president and CEO.

    About anthrax and anthrax immune globulin

    Anthrax infection, resulting from contact with spore-forming Bacillus
anthracis bacteria, occurs most commonly in herbivores such as sheep, cattle,
goats and camels. Human infections usually result from contact with infected
animals. Due to the stability of the infectious spores, however, anthrax is
considered to be a Category A biological agent. As well as through inhalation,
human anthrax infection can be acquired through the skin or by ingestion, and
in all forms fatality rates are high. Anthrax immune globulin is a hyperimmune
antibody product specific for Bacillus anthracis bacteria and has been
developed to treat inhalational anthrax.

    About Hyperimmunes

    Hyperimmunes are purified preparations of specific immune globulins
isolated from blood plasma. Immune globulins are the class of proteins that
function as antibodies. Cangene's proprietary manufacturing process allows it
to produce high-quality hyperimmune products aimed at a wide variety of
targets. The Company has been manufacturing its WinRho(R) SDF hyperimmune
product for more than 25 years, which has established the manufacturing
technology. As such, new Cangene hyperimmune products tend to enter the
regulatory process at a more advanced stage, which may shorten the development
time. Most recently, the Company's development efforts have been concentrated
on developing products with infectious disease and bioterrorism targets.

    About Cangene Corporation

    (more)Cangene is one of Canada's largest and earliest biopharmaceutical
companies. It was founded in 1984 and is headquartered in Winnipeg, Manitoba.
Cangene carries out research and development in Mississauga, Ontario and in
Winnipeg. It uses patented manufacturing processes to produce plasma-derived
and recombinant therapeutic proteins. Cangene has three FDA and Health
Canada-approved products and a fourth that has been approved in Canada only.
One of its recombinant protein products has received an approvable letter from
the FDA and another has been submitted for regulatory review in Canada. In
addition, the Company has several more products in development at various
stages.
    Capitalizing on its drug manufacturing expertise, Cangene also operates a
significant contract research and manufacturing business using its Winnipeg
facilities and the resources of Baltimore, Maryland-based Chesapeake
Biological Laboratories, Inc. (a wholly owned subsidiary). An expansion in
2006 at the Winnipeg location increased the Company's capacity to fractionate
plasma to accommodate the growing manufacturing requirements. Cangene's
website, www.cangene.com, includes product and investor information, including
past news releases. Chesapeake's website is www.cblinc.com.

    Forward-looking information
    The reader should be aware that Cangene's businesses are subject to risks
and uncertainties that cannot be predicted or quantified; consequently, actual
results may differ materially from past results and those expressed or implied
by any forward-looking statements. Factors that could cause or contribute to
such risks or uncertainties include, but are not limited to: the regulatory
environment including the difficulty of predicting regulatory outcomes;
changes in the value of the Canadian dollar; the Company's reliance on a small
number of customers including government organizations; the demand for new
products and the impact of competitive products, service and pricing;
availability and cost of raw materials, especially the cost, availability and
antibody concentration in plasma; fluctuations in operating results;
government policies or actions; progress and cost of clinical trials; reliance
on key strategic relationships; costs and possible development delays
resulting from use of legal, regulatory or legislative strategies by the
Company's competitors; uncertainty related to intellectual property protection
and potential cost associated with its defence; the Company's exposure to
lawsuits, and other matters beyond control of management.
    Risks and uncertainties are discussed more extensively in the MD&A
section of the Company's most recent annual report and annual information
form, which are available on the Company's website or on SEDAR at
www.sedar.com. Scientific information that relates to unapproved products or
unapproved uses of products is preliminary and investigative. No conclusions
can or should be drawn regarding the safety or efficacy of such products. Only
regulatory authorities can determine whether products are safe and effective
for the uses being investigated. Healthcare professionals are directed to
refer to approved labelling for products and not rely on information presented
in news releases.
    The cautionary statements referred to above should be considered in
connection with all written or oral statements, especially forward-looking
statements, that are made by the Company or by persons acting on its behalf
and in conjunction with its periodic filings with Securities Commissions,
including those contained in the Company's news releases and most recently
filed annual information form. Forward-looking statements can be identified by
the use of words such as "expects", "plans", "will", "believes", "estimates",
"intends", "may", "bodes" and other words of similar meaning (including
negative and grammatical variations). Should known or unknown risks or
uncertainties materialize, or should management's assumptions prove
inaccurate, actual results could vary materially from those anticipated. The
Company undertakes no obligation to publicly make or update any
forward-looking statements, except as required by applicable law.

    %SEDAR: 00002351E




For further information:

For further information: John McMillan at (204) 275-4310 or by email at
jmcmillan@cangene.com

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Cangene Corporation

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