A non-surgical intervention for double chins ~ a study published in the Journal of Drugs in Dermatology

NEW YORK, April 2, 2015 /CNW/ -- The Journal of Drugs in Dermatology is pleased to publish findings on a new injectable drug currently under development by Kythera Biopharmaceuticals, Inc. (Westlake Village, CA) that may provide a non-surgical alternative for people with double chins.

Double chins are clinically defined by accumulation of subcutaneous fat in the submental area. The result? A double chin that impacts perceptions of facial attractiveness. In "A Phase I Safety and Pharmacokinetic Study of ATX-101: Injectable, Synthetic Deoxycholic Acid for Submental Contouring," Patricia Walker MD PhD, Jere Fellmann PhD, and Paul F. Lizzul MD PhD MBA MPH explain how ATX-101 (deoxycholic acid [DCA] injection) has the potential to provide a less invasive alternative for submental fat reduction and contouring.  Both in vivo and in vitro studies show that, when injected into submental subcutaneous fat tissue, ATX-101 results in the targeted destruction of fat cells. The data support favorable safety and efficacy observations. Adverse events were bruising and swelling associated with the treatment area that are mild or moderate in severity. FDA approval for use of ATX-101 above the chest is expected in May 2015.

Quote from the authors:

'The results of this open-label phase I study indicate that injection of ATX-101 into subcutaneous fat is safe and well tolerated.'

Please find the article here.

About the Journal of Drugs in Dermatology

A product of SanovaWorks, the Journal of Drugs in Dermatology (JDD) is a full-color, peer-reviewed publication indexed with MEDLINE®/PubMed®. Founded by the renowned Dr. Perry Robins MD and now in its 12th year, JDD presents original articles, award-winning case reports, and timely features pertaining to new methods, techniques, and drug therapy in dermatology. Articles are reviewed by an International Editorial Board of over 150 renowned experts, led by Editor-in-Chief Dr. Perry Robins MD and Co-Editor-in-Chief Deborah S. Sarnoff MD. JDD has also been recognized as the official publication of the International Society of Dermatologic Surgery (ISDS), the Skin of Color Seminar Series (SOCSS) and the Orlando Dermatology Aesthetic and Clinical (ODAC) Conference. Visit JDDonline.com for article archives, access to CME activities, supplements, and author instructions. For more information, visit SanovaWorks.com and JDDonline.com.

Media Contact:
Karin Beehler

Logo - http://photos.prnewswire.com/prnh/20141203/162132

SOURCE Journal of Drugs in Dermatology

Organization Profile

Journal of Drugs in Dermatology

More on this organization

Kythera Biopharmaceuticals, Inc.

More on this organization

Custom Packages

Browse our custom packages or build your own to meet your unique communications needs.

Start today.

CNW Membership

Fill out a CNW membership form or contact us at 1 (877) 269-7890

Learn about CNW services

Request more information about CNW products and services or call us at 1 (877) 269-7890