EDMONTON, Jan. 24 /CNW/ - If University of Alberta medical professor Dr.
Richard Fedorak's research is correct, your urine sample may tell your
doctor if you have cancer in your colon.
He has discovered a number of biomarkers in urine that may prove to be a more accurate diagnostic tool to detect colonic
polyps before they become colon cancer than current stool/blood sample
analysis. Its accuracy may dramatically reduce the need for exploratory
colonoscopies or X-rays.
Metabolomics is a new area of medical research that tells doctors what
is happening in our bodies through metabolites (biomarkers) in human
waste including urine, stool, and breath.
Curious about metabolomics as a possible early detector of colon cancer,
Dr. Fedorak analyzed urine samples from patients enrolled in a 1200
subject clinical trial. He discovered a biomarker pattern collected
from the "front end" (urine) was an indicator of colonic polyps at the
To date, Dr. Fedorak's urine metabolomics has shown an 88% accuracy rate
in testing for colonic polyps, the precursor to colon cancer, which is
much higher than current tests. Once a polyp is identified it can
safely be removed with a colonoscopy.
With TEC Edmonton's help, Dr. Fedorak has formed Metabolomic
Technologies Inc www.metabolomictechnologies.ca
Dr. Fedorak will head up the scientific research. TEC Edmonton has
assisted in the complicated business of forming the company. The next
steps will involve raising investment dollars and ultimately marketing
the diagnostic tool once trials are complete.
The real win here is savings lives. Prevention of colon cancer in those
persons who have colonic polyps that are identified and removed is
nearly 100%. In contrast, if polyps are not detected they invariably
develop into colon cancer, the survival of which is less than 50 %.
Early diagnosis is the key, and a test like the one Dr. Fedorak is
developing may be the answer.
"Successful commercialization of MTI colon cancer test will benefit us
all," says Reg Joseph, MTI's newly appointed Chief Executive Officer,
"It's the kind of high-tech story that, if successful, will generate
considerable knowledge-economy jobs for young Edmontonians and save the
lives of many people."
TEC Edmonton helps transform high-tech discoveries into viable business
opportunities. Through our business services, TEC Edmonton helps
navigate the commercialization process by providing assistance with
technology evaluation, intellectual property protection, business plan
development, marketing research, corporate management and funding
preparation - as well as provides a home for startups in the TEC Centre
incubation facility. A unique non-for-profit enterprise, TEC Edmonton
is a joint venture between Edmonton Economic Development Corporation
(EEDC) and the University of Alberta. For more information visit www.TECedmonton.com
SOURCE TEC Edmonton
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