Prous Institute Presents Innovative Approach to Drug Discovery

    BARCELONA, Feb. 26 /CNW/ - Prous Institute for Biomedical Research today
presented its strategies for drug discovery on its newly designed website
( A large computational project with basic
research support and broad disease coverage is being developed at Prous
Institute under the broad-based Epistemic Drug Discovery(R) project.
    President and C.E.O. of the Institute, Dr. J.R. Prous, explained that "We
are committed to accelerating biomedical knowledge by the synchronization of
powerful expert knowledge-based systems and basic research. This
next-generation drug R&D force is expected to increase the efficiency and
efficacy of core drug R&D processes, facilitating continuous innovation."
    Two main drug discovery programs are being developed at the Institute.
One is focused on the design, synthesis and biological evaluation of new
small-molecule modulators of autophagy as therapeutic agents for cancer and
neurodegeneration (Alzheimer's disease and Huntington's disease). Another
program looks at target-driven drug discovery from natural sources, covering
type 2 diabetes, psychological stress and asthma. The Institute's
computational tools enable the in silico screening of thousands of natural
products in a rapid, reliable and cost-effective manner, as well as the
discovery of new targets and new uses for existing drugs.
    J.R. Prous commented "our approach is bringing us closer to drug
discovery, and the Institute expects to have several compounds in preclinical
evaluation by the end of this year (2009)."

    About Prous Institute for Biomedical Research

    Prous Institute is a privately-held research-driven organization
committed to the discovery and development of innovative therapies through the
use of its powerful computational tools and the support of basic research.
Prous Institute also fosters the development of prediction technologies used
for regulatory and industry safety screening programs. Prous Institute
receives several government grants and actively collaborates with academia and

For further information:

For further information: Prous Institute: Xavier Mensa, E-mail:, Tel: +34-93-457-17-95, or visit

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