National study measures how advanced maternal age affects mothers and
OTTAWA, Sept. 15, 2011 /CNW/ - While many older mothers have healthy
birth experiences, the risks associated with pregnancy and childbirth
start increasing at age 35 and rise significantly for mothers age 40
and older, according to a new study by the Canadian Institute for Health Information (CIHI). First-time mothers in their 40s are the most at risk for
delivery complications. In Due Time: Why Maternal Age Matters examined more than one million hospital births from 2006-2007 to
2008-2009 and is the largest population-based study of its kind in
Canada to measure the impact that advanced maternal age can have on
both mothers and their babies.
When looking at complications associated with pregnancy, CIHI's study
found that mothers age 40 and older are at least three times more
likely to develop gestational diabetes and placenta previa than younger
One in every 8 mothers older than 40 developed gestational diabetes,
compared with 1 in 12 age 35 to 39 and 1 in 24 age 20 to 34.
Gestational diabetes is high blood sugar that starts during pregnancy
and that can potentially cause high blood pressure for mothers as well
as delivery complications.
Placenta previa is a condition in which the placenta grows in the lowest
part of the uterus and covers all or part of the opening to the cervix.
One in every 65 mothers age 40 or older experienced this condition,
compared with 1 in 97 age 35 to 39 and 1 in 208 age 20 to 34. Placenta
previa can lead to delivery complications and potential health risks
for the child.
"Good prenatal care can help manage the risks associated with
gestational diabetes and placenta previa and ensure a healthy
delivery," explains Dr. Mark Walker, Senior Scientist, Ottawa Hospital
Research Institute; obstetrician, The Ottawa Hospital; and Research
Chair in Perinatal Epidemiology, University of Ottawa. "It is important
to understand the relationship with age in order to properly manage the
CIHI's study also measured the risk of labour and delivery complications
for older mothers. It found that two out of five (41.4%) mothers age 40
and older—and half (52.9%) of all first-time mothers in this age
group—had Caesarean section (C-section) deliveries. In comparison,
about one in three (35.3%) mothers age 35 to 39 and about one in four
(25.2%) age 20 to 34 gave birth by C-section.
Assisted vaginal deliveries, such as those requiring the use of forceps
or vacuum extraction, were also more common for older mothers with
single births. More than one out of three (34%) first-time mothers in
their 40s had an assisted delivery, compared with one-quarter (25.3%)
of first-time mothers age 20 to 34.
"In Canada, almost one in every five births is to a mother over the age
of 35, and this proportion is projected to continue to increase," says
Kathleen Morris, Director of Health System Analysis and Emerging Issues
at CIHI. "While most of these birth experiences are healthy and happy,
it's important for expectant mothers, their care providers and health
system planners to understand the risks associated with advanced
Babies born to older mothers more likely to face adverse birth outcomes
Advanced maternal age is widely known to be associated with chromosomal
disorders, such as Down syndrome. Over the three-year study period,
CIHI's data showed that 1 out of every 127 babies born to a mother age
40 and older had chromosomal disorders, compared with 1 out of 370
babies born to mothers 35 to 39 and 1 out of 1,000 babies whose mothers
were 20 to 34.
The risk of having a preterm birth (before the 37th week of pregnancy)
is also higher for older moms. The study found that 1 in 13 babies were
born prematurely to mothers age 20 to 34, compared with 1 in 11 in the
35-to-39 age group and 1 in 9 in the 40-and-older group. The hospital
cost of a preterm birth is seven to nine times higher than for a
full-term baby, according to 2005-2006 data from a previous CIHI
analysis. Premature babies have not had the chance to develop fully in
the womb and are more likely to face medical complications, ranging
from difficulty breathing, vision problems and intestinal problems to
neurological issues, such as cerebral palsy.
Mothers age 35 and older present additional costs to the health care
CIHI's study found that the cost of in-hospital births increases with a
mother's age, rising from an average of about $2,900 for mothers age 20
to 34 to about $3,000 for mothers age 35 to 39 and approximately $3,200
for mothers 40 and older.
Average hospital costs for babies were also highest for those whose
mothers were 40 and older, at about $1,800, compared with about $1,600
for mothers age 35 to 39 and approximately $1,500 for mothers age 20 to
34. These costs include care for birth defects, preterm births and
small-for-gestational-age births. These estimates for both mothers and
babies do not take into account any repeat hospitalizations or other
potential medical costs associated with a health problem at birth.
Physician and specialist fees are not included.
Rates of pregnancy and delivery complications for older mothers vary
across the country
According to the study, the proportion of women 35 and older having
babies varied across the provinces. Throughout the study period, more
than 1 out of 5 (22.3%) babies in British Columbia were born to mothers
age 35 and older, and a similar number (21%) of Ontario babies had
mothers age 35 and older. In New Brunswick, about 1 out of 8 (11.8%)
babies were born to mothers 35 and older, and 1 out of 10 (10.2%)
babies in Saskatchewan had mothers in that age group.
CIHI's study also showed variations in practice methods across the
country. C-section delivery rates for women 40 and older were highest
in Newfoundland and Labrador (47.9%) and British Columbia (45.6%) and
lowest in Saskatchewan and Quebec (35.3% each) and Manitoba (34.1%).
These variations are also reflected in women age 35 to 39. C-section
rates for these women varied from highs of 41.4% in Newfoundland and
Labrador and 37.8% in British Columbia to lows of 30.3% in Quebec and
28.9% in Manitoba. Women who deliver multiple babies have a higher
chance of delivering through a C-section; therefore, they were not
included in these provincial comparisons.
The report and the following figures and tables appear on our website at
Figure 1: Percentage of Women That Delivered Singletons via Caesarean
Delivery, by Jurisdiction and Maternal Age, Canada (Figure 5 in the
Table 1: Percentage of Live Births, by Maternal Age Group and
Jurisdiction, Canada (Table 5 in the analysis)
Table 2: Rates of Adverse Birth Outcomes and Birth Defects, by Maternal
Age Group, Canada (Table 8 in the analysis)
SOURCE CANADIAN INSTITUTE FOR HEALTH INFORMATION
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