MacDonald Mines Recommences Drilling Program on 5 Project Areas in Ring of Fire; Employs Advanced Modeling Process of Targets



    TORONTO, Sept. 22 /CNW/ - MacDonald Mines Exploration Ltd. (TSX
VENTURE:BMK) ("MacDonald" or the "Company") is pleased to announce it has
re-commenced it's 2008 drill program, focusing on multiple priority
geophysically defined targets across five project areas in the "Ring of Fire"
District of the James Bay Lowlands. The drill program will operate through to
the end of October 2008, with approximately 40 holes and approximately 8,000
metres drilled by program end.
    The drill program was paused at Labour Day weekend in order to give drill
and camp personnel a much-needed rest and catch up on core logging and
sampling. Core from August drilling has been sent to the labs for analysis.

    Drill Location Update

    Drilling began, and is still ongoing, on MacDonald's 100% owned McNugget
Property. The drill is scheduled to move to the next project zone as early as
next week once remaining targets have been drilled. The next project zone will
be "Wellington". The Company has agreed to rent the Fish Basket Camp from the
Summer Beaver First Nations, and will utilize this facility as a base camp for
exploration on the Wellington Property. A number of high priority targets have
been defined and modeled, and ready for drill testing.

    Advanced Modeling Process Now Being Employed

    MacDonald Mines has now fully engaged the use of an advanced modeling
process that will allow the Company to identify, prioritize and drill targets
without employing traditional ground geophysics. The benefits of this new
modeling process are significant to MacDonald's exploration process, as it now
allows the Company to efficiently locate targets at greater depths, with
improved accuracy, clarity and at significantly reduced costs.
    Since employing the new computer modeling techniques, the Company has
seen a dramatic increase in the percentage of successful "hits" of
mineralization on the most recent holes drilled, intersecting more sulphides
then the past and at greater depths. Through this modeling process, the
Company has been able to verify the conductive source of its targets in every
instance.
    Bill Nielsen, P.Geo, is the designated qualified person for the technical
information contained in this press release.

    WARNING: The statements made in this news release may contain
forward-looking statements that may involve a number of risks and
uncertainties. Actual events or results could differ materially from
expectations and projections set out herein.

    
    The TSX Venture Exchange does not accept responsibility for the adequacy
    or accuracy of this news release.
    

    %SEDAR: 00004560E




For further information:

For further information: MacDonald Mines Exploration Ltd., Email:
info@macdonaldmines.com, Website: www.macdonaldmines.com, (800) 818-5442,
(416) 364-4986, (416) 364-2753 (FAX), Brent Nykoliation, Director, Business
Development; J. A. Kirk McKinnon, President and CEO; Richard Schler, Vice
President & CFO

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MACDONALD MINES EXPLORATION LTD.

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