The role of dopamine in the hippocampus: toward a better understanding of schizophrenia

MONTREAL, April 3, 2014 /CNW Telbec/ - Bruno Giros, PhD, a researcher at the Douglas Mental Health University Institute and a professor in the Department of Psychiatry at McGill University, has demonstrated, for the first time, the role that dopamine plays in a region of the brain called the hippocampus. Published in Biological Psychiatry, this discovery opens the door to a better understanding of psychiatric diseases, such as schizophrenia.

Dopamine is a neurotransmitter that plays a central role in brain function, and many mental illnesses involve an imbalance in this chemical. What Bruno Giros has shown in particular is that dopamine is present in the hippocampus—the brain area associated with memory and learning—and that it plays a key role in this region.

"Our work helps us better understand some of the symptoms of schizophrenia for which the cause in the brain was unknown, particularly in the area of memory and learning. In a few years, this research could help researchers come up with new therapeutic approaches to improve these symptoms," explained Bruno Giros.

Dr. Giros is the Graham Boeckh Chair in Schizophrenia and the Canada Research Chair in Neurobiology of Mental Disorders. He is one of the world's leading scientists in the study and treatment of schizophrenia. In 1999, he created the Neurobiology and Psychiatry Laboratory at the Institut national de la santé et de la recherche médicale (INSERM) in France. He came to the Douglas Institute in 2008.

About the Douglas Institute – www.douglas.qc.ca

The Douglas is a world-class institute affiliated with McGill University and the World Health Organization. It treats people suffering from mental illness and offers them both hope and healing. Its teams of specialists and researchers are constantly increasing scientific knowledge, integrating this knowledge into patient care, and sharing it with the community in order to educate the public and eliminate prejudices surrounding mental health.

SOURCE Douglas Mental Health University Institute

For further information: and interviews: Florence Meney, Media Relations, Communications and Public Affairs Directorate, Douglas Mental Health University Institute,Dobell Pav.- 6875 LaSalle Blvd., B-2122 - Montreal, QC H4H 1R3, T. 514-761-6131, ext. 2769, Florence.meney@douglas.mcgill.ca